Protein Details: Aquaporin NIP1-2

Protein ID

ICDB_Pro_1272

Protein Name

Aquaporin NIP1-2

Gene Name

NIP1-2; NLM2; At4g18910; F13C5.80

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

294 amino acids

AlphaFoldDB

AF-Q8LFP7-F1-model_v4.pdb

Function

Water channel probably required to promote glycerol permeability and water transport across cell membranes.

Sequence

MAEISGNGGDARDGAVVVNLKEEDEQQQQQQAIHKPLKKQDSLLSISVPFLQKLMAEVLGTYFLIFAGCAAVAVNTQHDKAVTLPGIAIVWGLTVMVLVYSLGHISGAHFNPAVTIAFASCGRFPLKQVPAYVISQVIGSTLAAATLRLLFGLDQDVCSGKHDVFVGTLPSGSNLQSFVIEFIITFYLMFVISGVATDNRAIGELAGLAVGSTVLLNVIIAGPVSGASMNPGRSLGPAMVYSCYRGLWIYIVSPIVGAVSGAWVYNMVRYTDKPLREITKSGSFLKTVRNGSSR

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed in developing seeds.

DOI ID

10.1016/s0014-5793(00)02027-5; 10.1038/47134; 10.1111/tpj.13415; 10.1126/science.1088305; 10.1186/gb-2001-3-1-research0001

RefSeq

NP_193626.1